Glycan-related (non-GT or GH) Families: Sulfotransferases and HS epimerase

Members of the respective protein family are listed below with corresponding annotation information. For detailed design information for expression constructs click the gene symbol to navigate to the respective gene record.

Gene Symbol Uniprot GeneID UniProt Annotation
CHST1 O43916 8534 Carbohydrate sulfotransferase 1; Keratan sulfate Gal-6 sulfotransferase
CHST2 Q9Y4C5 9435 Carbohydrate sulfotransferase 2: N-acetylglucosamine 6-O-sulfotransferase 1
CHST3 Q7LGC8 9469 Carbohydrate sulfotransferase 3: Chondroitin 6-O-sulfotransferase 1
CHST4 Q8NCG5 10164 Carbohydrate sulfotransferase 4: synthesis of SELL ligand sialyl 6-sulfo Lewis X
CHST5 Q9GZS9 23563 Carbohydrate sulfotransferase 5: synthesis of GlcNAc-6-SO4 on mucins
CHST6 Q9GZX3 4166 Carbohydrate sulfotransferase 6: synthesis of GlcNAc-6-SO4 on keratan sulfate.
CHST7 Q9NS84 56548 Carbohydrate sulfotransferase 7: synthesis of GlcNAc-6-SO4 on wide range of acceptors (not keratan)
CHST8 Q9H2A9 64377 Carbohydrate sulfotransferase 8: synthesis of GlcNAc-4-SO4 on N- and O-glycans, esp glycoprotein hormones
CHST9 Q7L1S5 83539 Carbohydrate sulfotransferase 9: synthesis of GlcNAc-4-SO4 on N- and O-glycans, esp glycoprotein hormones
CHST10 O43529 9486 Carbohydrate sulfotransferase 10: HNK-1 sulfotransferase
CHST11 Q9NPF2 50515 Carbohydrate sulfotransferase 11: Chondroitin 4-O-sulfotransferase 1
CHST12 Q9NRB3 55501 Carbohydrate sulfotransferase 12: Chondroitin 4-O-sulfotransferase 2
CHST13 Q8NET6 166012 Carbohydrate sulfotransferase 13: Chondroitin 4-O-sulfotransferase 3
CHST14 Q8NCH0 113189 Carbohydrate sulfotransferase 14: synthesis of GalNAc-4-SO4  in dermatan sulfate
CHST15 Q7LFX5 51363 Carbohydrate sulfotransferase 15: transfers to 6 position of GalNAc4-SO4 in chondroitin sulfate 
GAL3ST1 Q99999 9514 Galactosylceramide sulfotransferase
GAL3ST2 Q9H3Q3 64090 Galactose-3-O-sulfotransferase 2: acts on both type 1 and type 2 chain termini
GAL3ST3 Q96A11 89792 Galactose-3-O-sulfotransferase 3: acts on terminal LacNAc chains, preferring type 2 chain termini
GAL3ST4 Q96RP7 79690 Galactose-3-O-sulfotransferase 4: acts on O-linked core 1 and core 2 glycans
HS2ST1 Q7LGA3 9653 Heparan sulfate 2-O-sulfotransferase 1
HS3ST1 O14792 9957 Heparan sulfate glucosamine 3-O-sulfotransferase 1
HS3ST2 Q9Y278 9956 Heparan sulfate glucosamine 3-O-sulfotransferase 2
HS3ST3A1 Q9Y663 9955 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1
HS3ST3B1 Q9Y662 9953 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1
HS3ST4 Q9Y661 9951 Heparan sulfate glucosamine 3-O-sulfotransferase 4
HS3ST5 Q8IZT8 222537 Heparan sulfate glucosamine 3-O-sulfotransferase 5
HS3ST6 Q96QI5 64711 Heparan sulfate glucosamine 3-O-sulfotransferase 6
HS6ST1 O60243 9394 Heparan-sulfate 6-O-sulfotransferase 1
HS6ST2 Q96MM7 90161 Heparan-sulfate 6-O-sulfotransferase 2
HS6ST3 Q8IZP7 266722 Heparan-sulfate 6-O-sulfotransferase 3
NDST1 P52848 3340 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
NDST2 P52849 8509 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2
NDST3 O95803 9348 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3
NDST4 Q9H3R1 64579 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
UST A8KA57 10090 Uronyl 2-sulfotransferase

 

GLCE O94923 26035 D-glucuronyl C5-epimerase